Erythritol catabolism by Brucella abortus

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The genes for erythritol catabolism are organized as an inducible operon in Brucella abortus.

Erythritol utilization is a characteristic of pathogenic Brucella abortus strains. The attenuated vaccine strain B19 is the only Brucella strain that is inhibited by erythritol, so a role for erythritol metabolism in virulence is suspected. A chromosomal fragment from the pathogenic strain B. abortus 2308 containing genes for the utilization of erythritol was cloned taking advantage of an eryth...

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Evaluation of the Effects of Erythritol on Gene Expression in Brucella abortus

Bacteria of the genus Brucella have the unusual capability to catabolize erythritol and this property has been associated with their virulence mainly because of the presence of erythritol in bovine foetal tissues and because the attenuated S19 vaccine strain is the only Brucella strain unable to oxydize erythritol. In this work we have analyzed the transcriptional changes produced in Brucella b...

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Killing of Brucella abortus by bovine serum.

Studies of the serum bactericidal system in bovine brucellosis were undertaken to investigate the role of the humoral immune response in protection of cattle against the facultative intracellular parasite Brucella abortus. Fresh sera from normal control cattle, infected cattle, and cattle immunized with B. abortus cell envelopes were collected before treatment and during the course of immunizat...

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Pantothenic acid synthesis by smooth Brucella abortus.

The relationship between formation of exogenous alanine and the establishment of nonsmooth variants in originally smooth cultures of Brucella abortus strains has been clearly demonstrated (Goodlow et al., 1950). Furthermore, the addition of D-alanine to smooth cultures in synthetic medium (Gerhardt and Wilson, 1948) results in earlier establishment of nonsmooth cells (Goodlow et al., 1951). Sub...

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Brucella abortus endocarditis.

T HE purpose of this report is to describe the successful treatment of a case of bacterial endocarditis due to Brucella abortus. As far as I have been able to discover at the date of writing, no successfully treated case of this disease has been reported previously, with the exception of a case of mixed bacterial endocarditis presented in 1954 by Quinn and Brown.' A second case of treated Br. a...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 1975

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.121.2.619-630.1975